The elevated polyamines, amine-rich molecules with diverse functions in pathophysiology processes, are implicated in contributing to tumorigenesis and progression.Whether and how they affect the efficacy of chemotherapy is incompletely understood.Our screening assays reveal that the supplement with a low dose of spermidine (Spd), one of the polyami
ObjectiveTo evaluate the clinical outcomes and maternal-neonatal safety of gonadotropin releasing hormone antagonist (GnRH-ant) and gonadotropin releasing hormone agonist (GnRH-a) protocols.MethodsA total of 2505 women undergoing their first in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) were retrospectively analyzed.Patients
Seed dormancy controls germination Hip Flasks and plays a critical role in regulating the beginning of the life cycle of plants.Seed dormancy is established and maintained during seed maturation and is gradually broken during dry storage (after-ripening).The plant hormone abscisic acid (ABA) and DELAY OF GERMINATION1 (DOG1) protein are essential re
When environmental processes cut across socioeconomic boundaries, traditional top-down government approaches struggle to effectively manage and conserve ecosystems.In such cases, governance arrangements that foster multiactor collaboration are needed.The effectiveness of such arrangements, however, depends on how well any ecological interdependenci